Sangha was a surprise selection in Australia's preliminary squad for the 13th edition of the World Cup in India later this year and the leg-spinner displayed some match-winning qualities as he collected the superb figures of 4/31 in the opening match of the three-game series against the Proteas.
It was a dream debut for Sangha, who picked up the vital wickets of Aiden Markram, Dewald Brevis, Tristan Stubbs and Marco Jansen as Australia registered a comprehensive 111-run victory.
Sangha only received a late call-up to Australia's XI when first-choice spinner Adam Zampa was struck down with illness on the morning of the match and the 21-year-old put in a performance that will put him in the mix to make his side's final squad of 15 players for the World Cup.
Australia captain Mitch Marsh - who top-scored for the tourists with a quickfire 91 - was full of praise for Sangha and believes the right-armer has a long and prosperous international career ahead.
"He's a fantastic young talent. To come in and do that, he's got great character, and he's going to fit right into international cricket," Marsh said after the win.